Polytechnic Institute
of Bragança



CIMO - Mountain Research Center. See video HERE


Cristina Sofia Gomes Caleja

Junior Researcher
Group: Sustainable Processes and Products
Phone: 273303419
ORCID: 0000-0002-5769-8484
Scopus Author ID: 36514202500


  • 2018 - PhD in Sustainable Chemistry, Faculdade de Ciências da Universidade do Porto, Porto, Portugal
  • 2010 - in Laboratory Analysis, Universidade de Trás-os-Montes e Alto Douro, Portugal
  • 2008 - in Biology, Universidade de Trás-os-Montes e Alto Douro, Portugal

Awards and Honors

  • 2017 - Prémio de melhor comunicação, IX Congresso Ibérico de Agroengenharia


  • Extraction, identification, fractionation and isolation of chemical compounds in natural matrices
  • Development of natural ingredients and innovative food formulations with functional properties
  • Incorporation of plant extracts in food formulations adding natural bioactive constituents and removing synthetic compounds frequently related to health risks


GreenHealth - Estratégias digitais baseadas em ativos biológicos para melhorar o bem-estar e promover a saúde verde
Funding body: FEDER
Reference: Norte-01-0145-FEDER-000042
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-10-01
End: 2023-09-30
HealthyPETFOOD - Formulações PetFood para promoção da saúde e qualidade de vida
Funding body: POCI-FEDER
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-01-10
End: 2023-06-30
PreVineGrape - Desenvolvimento de um biofungicida para combate a doenças da videira
Funding body: POCI-FEDER
Principal Investigator:Sandrina Alves Heleno
Start: 2021-01-01
End: 2023-06-29
BIOma - Soluções integradas de BIOeconomia para a Mobilização cadeia Agroalimentar
Funding body: Portugal 2020
Reference: POCI-1-0247-FEDER-046112
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-07-01
End: 2023-06-03
VALORNATURAL - Valorização de Recursos Naturais através da Extração de Ingredientes de Elevado Valor Acrescentado para Aplicações na Indústria Alimentar
Funding body: PORTUGAL 2020- SI-IDT - Programas mobilizadores
Principal Investigator:Lillian Bouçada de Barros
Start: 2018-09-01
End: 2022-08-31

Total results: 48
Menezes B.,Caleja C.,Calhelha R.C.,Pinela J.,Dias M.I.,Stojković D.,Soković M.,Gonçalves O.H.,Leimann F.V.,Pereira E.,Barros L.
Use of Bio-Waste of Ilex paraguariensis A. St. Hil. (Yerba mate) to Obtain an Extract Rich in Phenolic Compounds with Preservative Potential
Foods, 12, , 2023

Pires E.d.O.,Di Gioia F.,Rouphael Y.,García-Caparrós P.,Tzortzakis N.,Ferreira I.C.F.R.,Barros L.,Petropoulos S.A.,Caleja C.
Edible flowers as an emerging horticultural product: A review on sensorial properties, mineral and aroma profile
Trends in Food Science and Technology, 137, 31-54, 2023

Brandão A.S.,Caleja C.,Dias M.I.,Ben Salha A.,Rezouga F.,Rodrigues P.,Ferreira I.C.F.R.,Barros L.,Santos J.M.R.C.A.
Valorization of pomace from craft cider: Nutritional value, chemical composition, and phenolic and mineral profiles
eFood, 4, , 2023

Oliveira T.C.G.,Caleja C.,Oliveira M.B.P.P.,Pereira E.,Barros L.
Reuse of fruits and vegetables biowaste for sustainable development of natural ingredients
Food Bioscience, 53, , 2023

Silva B.N.,Cadavez V.,Caleja C.,Pereira E.,Calhelha R.C.,Añibarro-Ortega M.,Finimundy T.,Kostić M.,Soković M.,Teixeira J.A.,Barros L.,Gonzales-Barron U.
Phytochemical Composition and Bioactive Potential of Melissa officinalis L., Salvia officinalis L. and Mentha spicata L. Extracts
Foods, 12, , 2023

Pereira E.,Fernandes F.A.,Mandim F.,Ayuso M.,Ferreira I.C.F.R.,Caleja C.,Barros L.
Non-alkaloid nitrogen containing compounds
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 331-362, 2023

Caleja C.,Pereira E.,Ferreira I.C.F.R.,Barros L.
High-added-value compounds from agro-food industry wastewater
Advanced Technologies in Wastewater Treatment: Food Processing Industry, 1-24, 2023

Pinela J.,Fuente B.d.l.,Rodrigues M.,Pires T.C.S.P.,Mandim F.,Almeida A.,Dias M.I.,Caleja C.,Barros L.
Upcycling Fish By-Products into Bioactive Fish Oil: The Suitability of Microwave-Assisted Extraction
Biomolecules, 13, , 2023

Rugolo M.,Mascoloti Spréa R.,Dias M.I.,Pires T.C.S.P.,Añibarro-Ortega M.,Barroetaveña C.,Caleja C.,Barros L.
Nutritional Composition and Bioactive Properties of Wild Edible Mushrooms from Native Nothofagus Patagonian Forests
Foods, 11, , 2022

de la Fuente B.,Pinela J.,Calhelha R.C.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Sea bass (Dicentrarchus labrax) and sea bream (Sparus aurata) head oils recovered by microwave-assisted extraction: Nutritional quality and biological properties
Food and Bioproducts Processing, 136, 97-105, 2022

Mascoloti Spréa R.,Caleja C.,Pinela J.,Finimundy T.C.,Calhelha R.C.,Kostić M.,Sokovic M.,Prieto M.A.,Pereira E.,Amaral J.S.,Barros L.
Comparative study on the phenolic composition and in vitro bioactivity of medicinal and aromatic plants from the Lamiaceae family
Food Research International, 161, , 2022

Garcia-Oliveira P.,Carreira-Casais A.,Pereira E.,Dias M.I.,Pereira C.,Calhelha R.C.,Stojković D.,Sokovic M.,Simal-Gandara J.,Prieto M.A.,Caleja C.,Barros L.
From Tradition to Health: Chemical and Bioactive Characterization of Five Traditional Plants
Molecules, 27, , 2022

Moreira B.,Pereira E.,Finimundy T.C.,Pinela J.,Calhelha R.C.,Carocho M.,Stojković D.,Sokovic M.,Ferreira I.C.F.R.,Caleja C.,Barros L.
Pineapple by-products as a source of bioactive compounds with potential for industrial food application
Food and Function, 13, 9959-9972, 2022

de la Fuente B.,Pinela J.,Mandim F.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Nutritional and bioactive oils from salmon (Salmo salar) side streams obtained by Soxhlet and optimized microwave-assisted extraction
Food Chemistry, 386, , 2022

López-Hortas L.,Caleja C.,Pinela J.,Petrović J.,Soković M.,Ferreira I.C.F.R.,Torres M.D.,Domínguez H.,Pereira E.,Barros L.
Comparative evaluation of physicochemical profile and bioactive properties of red edible seaweed Chondrus crispus subjected to different drying methods
Food Chemistry, 383, , 2022

Pires E.d.O.,Di Gioia F.,Rouphael Y.,Ferreira I.C.F.R.,Caleja C.,Barros L.,Petropoulos S.A.
The compositional aspects of edible flowers as an emerging horticultural product
Molecules, 26, , 2021

Carvalho A.S.d.,Rezende S.C.d.,Caleja C.,Pereira E.,Barros L.,Fernandes I.,Manrique Y.A.,Gonçalves O.H.,Ferreira I.C.F.R.,Barreiro M.F.
β-Carotene colouring systems based on solid lipid particles produced by hot melt dispersion
Food Control, 129, , 2021

Pires E.O.,Caleja C.,Garcia C.C.,Ferreira I.C.F.R.,Barros L.
Current status of genus Impatiens: Bioactive compounds and natural pigments with health benefits
Trends in Food Science and Technology, 117, 106-124, 2021

Pires E.d.O.,Pereira E.,Carocho M.,Pereira C.,Dias M.I.,Calhelha R.C.,Ćirić A.,Soković M.,Garcia C.C.,Ferreira I.C.F.R.,Caleja C.,Barros L.
Study on the potential application of impatiens balsamina l. Flowers extract as a natural colouring ingredient in a pastry product
International Journal of Environmental Research and Public Health, 18, , 2021

Giordano M.,Pinela J.,Dias M.I.,Calhelha R.C.,Stojković D.,Soković M.,Tavares D.,Cánepa A.L.,Ferreira I.C.F.R.,Caleja C.,Barros L.
Ultrasound-assisted extraction of flavonoids from kiwi peel: Process optimization and bioactivity assessment
Applied Sciences (Switzerland), 11, , 2021

Alaya I.B.,Pereira E.,Dias M.I.,Pinela J.,Calhelha R.C.,Soković M.,Kostić M.,Prieto M.A.,Essid F.,Caleja C.,Ferreira I.C.F.R.,Barros L.
Development of a natural preservative from chestnut flowers: Ultrasound-assisted extraction optimization and functionality assessment
Chemosensors, 9, , 2021

Carpena M.,Caleja C.,Pereira E.,Pereira C.,Ćirić A.,Soković M.,Soria-Lopez A.,Fraga-Corral M.,Simal-Gandara J.,Ferreira I.C.F.R.,Barros L.,Prieto M.A.
Red seaweeds as a source of nutrients and bioactive compounds: Optimization of the extraction
Chemosensors, 9, , 2021

Alves E.,Ntungwe E.N.,Gregório J.,Rodrigues L.M.,Pereira-Leite C.,Caleja C.,Pereira E.,Barros L.,Aguilar-Vilas M.V.,Rosado C.,Rijo P.
Characterization of kefir produced in household conditions: Physicochemical and nutritional profile, and storage stability
Foods, 10, , 2021

Pires E.d.O.,Pereira E.,Pereira C.,Dias M.I.,Calhelha R.C.,Ćirić A.,Soković M.,Hassemer G.,Garcia C.C.,Caleja C.,Barros L.,Ferreira I.C.F.R.
Chemical composition and bioactive characterisation of Impatiens walleriana
Molecules, 26, , 2021

Finimundy T.C.,Pereira C.,Dias M.I.,Caleja C.,Calhelha R.C.,Sokovic M.,Stojković D.,Carvalho A.M.,Rosa E.,Barros L.,Ferreira I.C.F.R.
Infusions of herbal blends as promising sources of phenolic compounds and bioactive properties
Molecules, 25, , 2020

Caleja C.,Barros L.,Barreira J.C.M.,Soković M.,Calhelha R.C.,Bento A.,Oliveira M.B.P.P.,Ferreira I.C.F.R.
Castanea sativa male flower extracts as an alternative additive in the Portuguese pastry delicacy "pastel de nata"
Food and Function, 11, 2208-2217, 2020

Pires T.C.S.P.,Caleja C.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
Vaccinium myrtillus l. Fruits as a novel source of phenolic compounds with health benefits and industrial applications-a review
Current Pharmaceutical Design, 26, 1917-1928, 2020

da Silva Veloso F.,Caleja C.,Calhelha R.C.,Pires T.C.S.,Alves M.J.,Barros L.,Genena A.K.,Barreira J.C.M.,Ferreira I.C.F.R.
Characterization and application of pomegranate epicarp extracts as functional ingredients in a typical Brazilian pastry product
Molecules, 25, , 2020

Dias M.,Caleja C.,Pereira C.,Calhelha R.C.,Kostic M.,Sokovic M.,Tavares D.,Baraldi I.J.,Barros L.,Ferreira I.C.F.R.
Chemical composition and bioactive properties of byproducts from two different kiwi varieties
Food Research International, 127, , 2020

Caleja C.,Finimundy T.C.,Pereira C.,Barros L.,Calhelha R.C.,Sokovic M.,Ivanov M.,Carvalho A.M.,Rosa E.,Ferreira I.C.F.R.
Challenges of traditional herbal teas: Plant infusions and their mixtures with bioactive properties
Food and Function, 10, 5939-5951, 2019

Jabeur I.,Pereira E.,Caleja C.,Calhelha R.C.,Soković M.,Catarino L.,Barros L.,Ferreira I.C.F.R.
Exploring the chemical and bioactive properties of: Hibiscus sabdariffa L. calyces from Guinea-Bissau (West Africa)
Food and Function, 10, 2234-2243, 2019

Caleja C.,Barros L.,Prieto M.A.,Bento A.,Oliveira M.B.P.P.,Ferreira I.C.F.R.
Development of a natural preservative obtained from male chestnut flowers: Optimization of a heat-assisted extraction technique
Food and Function, 10, 1352-1363, 2019

López C.J.,Caleja C.,Prieto M.A.,Sokovic M.,Calhelha R.C.,Barros L.,Ferreira I.C.F.R.
Stability of a cyanidin-3-O-glucoside extract obtained from Arbutus unedo L. and incorporation into wafers for colouring purposes
Food Chemistry, 275, 426-438, 2019

López C.J.,Caleja C.,Prieto M.A.,Barreiro M.F.,Barros L.,Ferreira I.C.F.R.
Optimization and comparison of heat and ultrasound assisted extraction techniques to obtain anthocyanin compounds from Arbutus unedo L. Fruits
Food Chemistry, 264, 81-91, 2018

Caleja C.,Barros L.,Barreira J.C.M.,Ciric A.,Sokovic M.,Calhelha R.C.,Beatriz M.,Oliveira P.P.,Ferreira I.C.F.R.
Suitability of lemon balm (Melissa officinalis L.) extract rich in rosmarinic acid as a potential enhancer of functional properties in cupcakes
Food Chemistry, 250, 67-74, 2018

Takwa S.,Caleja C.,Barreira J.C.M.,Soković M.,Achour L.,Barros L.,Ferreira I.C.F.R.
Arbutus unedo L. and Ocimum basilicum L. as sources of natural preservatives for food industry: A case study using loaf bread
LWT, 88, 47-55, 2018

Caleja C.,Ribeiro A.,Barreiro M.F.,Ferreira I.C.F.R.
Phenolic compounds as nutraceuticals or functional food ingredients
Current Pharmaceutical Design, 23, 2787-2806, 2017

Caleja C.,Barros L.,Antonio A.L.,Oliveira M.B.P.P.,Ferreira I.C.F.R.
A comparative study between natural and synthetic antioxidants: Evaluation of their performance after incorporation into biscuits
Food Chemistry, 216, 342-346, 2017

Caleja C.,Barros L.,Prieto M.A.,Barreiro M.F.,Oliveira M.B.P.P.,Ferreira I.C.F.R.
Extraction of rosmarinic acid from Melissa officinalis L. by heat-, microwave- and ultrasound-assisted extraction techniques: A comparative study through response surface analysis
Separation and Purification Technology, 186, 297-308, 2017

Pinela J.,Carocho M.,Dias M.I.,Caleja C.,Barros L.,Ferreira I.C.F.R.
Wild Plant-Based Functional Foods, Drugs, and Nutraceuticals
Wild Plants, Mushrooms and Nuts: Functional Food Properties and Applications, 315-351, 2016

Caleja C.,Barros L.,Antonio A.L.,Carocho M.,Oliveira M.B.P.P.,Ferreira I.C.F.R.
Fortification of yogurts with different antioxidant preservatives: A comparative study between natural and synthetic additives
Food Chemistry, 210, 262-268, 2016

Caleja C.,Ribeiro A.,Barros L.,Barreira J.C.M.,Antonio A.L.,Oliveira M.B.P.P.,Barreiro M.F.,Ferreira I.C.F.R.
Cottage cheeses functionalized with fennel and chamomile extracts: Comparative performance between free and microencapsulated forms
Food Chemistry, 199, 720-726, 2016

Ribeiro A.,Caleja C.,Barros L.,Santos-Buelga C.,Barreiro M.F.,Ferreira I.C.F.R.
Rosemary extracts in functional foods: Extraction, chemical characterization and incorporation of free and microencapsulated forms in cottage cheese
Food and Function, 7, 2185-2196, 2016

Caleja C.,Barros L.,Antonio A.L.,Ciric A.,Barreira J.C.M.,Sokovic M.,Oliveira M.B.P.P.,Santos-Buelga C.,Ferreira I.C.F.R.
Development of a functional dairy food: Exploring bioactive and preservation effects of chamomile (Matricaria recutita L.)
Journal of Functional Foods, 16, 114-124, 2015

Caleja C.,Barros L.,Antonio A.L.,Ciric A.,Soković M.,Oliveira M.B.P.P.,Santos-Buelga C.,Ferreira I.C.F.R.
Foeniculum vulgare Mill. As natural conservation enhancer and health promoter by incorporation in cottage cheese
Journal of Functional Foods, 12, 428-438, 2015

Vieira-Pinto M.,Morais L.,Caleja C.,Themudo P.,Torres C.,Igrejas G.,Poeta P.,Martins C.
Salmonella sp. in game (Sus scrofa and Oryctolagus cuniculus)
Foodborne Pathogens and Disease, 8, 739-740, 2011

Caleja C.,de Toro M.,Gonçalves A.,Themudo P.,Vieira-Pinto M.,Monteiro D.,Rodrigues J.,Sáenz Y.,Carvalho C.,Igrejas G.,Torres C.,Poeta P.
Antimicrobial resistance and class I integrons in Salmonella enterica isolates from wild boars and Bísaro pigs
International Microbiology, 14, 19-24, 2011

Pinto L.,Poeta P.,Vieira S.,Caleja C.,Radhouani H.,Carvalho C.,Vieira-Pinto M.,Themudo P.,Torres C.,Vitorino R.,Domingues P.,Igrejas G.
Genomic and proteomic evaluation of antibiotic resistance in Salmonella strains
Journal of Proteomics, 73, 1535-1541, 2010