O Norte Somos Nós

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Polytechnic Institute
of Bragança



María Fraga Corral

Group: Sustainable Processes and Products
ORCID: 0000-0002-5663-9239
Scopus Author ID: 56346469200


  • Since 2019: post-doctoral researcher at Universidade de Vigo (Spain) and CIMO (Portugal).
  • 2016 - 2018: post-doctoral researcher at Teagasc (Ireland) and at Universidade de Vigo (Ourense, Spain).


  • 2015 - PhD in Biology, University of Vigo
  • 2011 - Master degree in Basic and Applied Research in Veterinary Sciences, University of Vigo
  • 2009 - First degree in Biology, University of Vigo


  • Detection methods (analytical and biomolecular assays), natural compounds, natural products, functional food, circular economy
  • Food safety, public health

Total results: 46
Lourenço-Lopes C.,Fraga-Corral M.,Soria-Lopez A.,Nuñes-Estevez B.,Barral-Martinez M.,Silva A.,Li N.,Liu C.,Simal-Gandara J.,Prieto M.A.
Fucoxanthin’s Optimization from Undaria pinnatifida Using Conventional Heat Extraction, Bioactivity Assays and In Silico Studies
Antioxidants, 11, , 2022

Chamorro F.,Carpena M.,Fraga-Corral M.,Echave J.,Riaz Rajoka M.S.,Barba F.J.,Cao H.,Xiao J.,Prieto M.A.,Simal-Gandara J.
Valorization of kiwi agricultural waste and industry by-products by recovering bioactive compounds and applications as food additives: A circular economy model
Food Chemistry, 370, , 2022

Garcia-Perez P.,Lourenço-Lopes C.,Silva A.,Pereira A.G.,Fraga-Corral M.,Zhao C.,Xiao J.,Simal-Gandara J.,Prieto M.A.
Pigment Composition of Nine Brown Algae from the Iberian Northwestern Coastline: Influence of the Extraction Solvent
Marine Drugs, 20, , 2022

Fraga-Corral M.,Ronza P.,Garcia-Oliveira P.,Pereira A.G.,Losada A.P.,Prieto M.A.,Quiroga M.I.,Simal-Gandara J.
Aquaculture as a circular bio-economy model with Galicia as a study case: How to transform waste into revalorized by-products
Trends in Food Science and Technology, 119, 23-35, 2022

García-Oliveira P.,Fraga-Corral M.,Pereira A.G.,Prieto M.A.,Simal-Gandara J.
Solutions for the sustainability of the food production and consumption system
Critical Reviews in Food Science and Nutrition, 62, 1765-1781, 2022

Fraga-Corral M.,Carpena M.,Garcia-Oliveira P.,Pereira A.G.,Prieto M.A.,Simal-Gandara J.
Analytical Metabolomics and Applications in Health, Environmental and Food Science
Critical Reviews in Analytical Chemistry, 52, 712-734, 2022

Lourenço-Lopes C.,Fraga-Corral M.,Jimenez-Lopez C.,Carpena M.,Pereira A.G.,Garcia-Oliveira P.,Prieto M.A.,Simal-Gandara J.
Biological action mechanisms of fucoxanthin extracted from algae for application in food and cosmetic industries
Trends in Food Science and Technology, 117, 163-181, 2021

Echave J.,Fraga-Corral M.,Garcia-Perez P.,Popović-Djordjević J.,Avdović E.H.,Radulović M.,Xiao J.,Prieto M.A.,Simal-Gandara J.
Seaweed protein hydrolysates and bioactive peptides: Extraction, purification, and applications
Marine Drugs, 19, , 2021

Barral-Martinez M.,Fraga-Corral M.,Garcia-Perez P.,Simal-Gandara J.,Prieto M.A.
Almond by-products: Valorization for sustainability and competitiveness of the industry
Foods, 10, , 2021

Carpena M.,Caleja C.,Pereira E.,Pereira C.,Ćirić A.,Soković M.,Soria-Lopez A.,Fraga-Corral M.,Simal-Gandara J.,Ferreira I.C.F.R.,Barros L.,Prieto M.A.
Red seaweeds as a source of nutrients and bioactive compounds: Optimization of the extraction
Chemosensors, 9, , 2021

Garcia-Oliveira P.,Barral M.,Carpena M.,Gullón P.,Fraga-Corral M.,Otero P.,Prieto M.A.,Simal-Gandara J.
Traditional plants from Asteraceae family as potential candidates for functional food industry
Food and Function, 12, 2850-2873, 2021

Pereira A.G.,Fraga-Corral M.,Garcia-Oliveira P.,Lourenço-Lopes C.,Carpena M.,Prieto M.A.,Simal-Gandara J.
The use of invasive algae species as a source of secondary metabolites and biological activities: Spain as case-study
Marine Drugs, 19, , 2021

Jimenez-Lopez C.,Pereira A.G.,Lourenço-Lopes C.,Garcia-Oliveira P.,Cassani L.,Fraga-Corral M.,Prieto M.A.,Simal-Gandara J.
Main bioactive phenolic compounds in marine algae and their mechanisms of action supporting potential health benefits
Food Chemistry, 341, , 2021

Pereira A.G.,Otero P.,Fraga-Corral M.,Garcia-Oliveira P.,Carpena M.,Prieto M.A.,Simal-Gandara J.
State-of-the-art of analytical techniques to determine food fraud in olive oils
Foods, 10, 1-24, 2021

Garcia-Oliveira P.,Jimenez-Lopez C.,Lourenço-Lopes C.,Chamorro F.,Pereira A.G.,Carrera-Casais A.,Fraga-Corral M.,Carpena M.,Simal-Gandara J.,Prieto M.A.
Evolution of flavors in extra virgin olive oil shelf-life
Antioxidants, 10, 1-20, 2021

Fraga-Corral M.,Otero P.,Cassani L.,Echave J.,Garcia-Oliveira P.,Carpena M.,Chamorro F.,Lourenço-Lopes C.,Prieto M.A.,Simal-Gandara J.
Traditional applications of tannin rich extracts supported by scientific data: Chemical composition, bioavailability and bioaccessibility
Foods, 10, , 2021

Echave J.,Barral M.,Fraga-Corral M.,Prieto M.A.,Simal-Gandara J.
Bottle aging and storage of wines: A review
Molecules, 26, , 2021

Garcia-Oliveira P.,Otero P.,Pereira A.G.,Chamorro F.,Carpena M.,Echave J.,Fraga-Corral M.,Simal-Gandara J.,Prieto M.A.
Status and challenges of plant-anticancer compounds in cancer treatment
Pharmaceuticals, 14, 1-28, 2021

Garcia-Oliveira P.,Fraga-Corral M.,Carpena M.,Prieto M.A.,Simal-Gandara J.
Approaches for sustainable food production and consumption systems
Future Foods: Global Trends, Opportunities, and Sustainability Challenges, 23-38, 2021

Otero P.,Carpena M.,Garcia-Oliveira P.,Echave J.,Soria-Lopez A.,Garcia-Perez P.,Fraga-Corral M.,Cao H.,Nie S.,Xiao J.,Simal-Gandara J.,Prieto M.A.
Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties
Critical Reviews in Food Science and Nutrition, , 2021

Carpena M.,Fraga-Corral M.,Otero P.,Nogueira R.A.,Garcia-Oliveira P.,Prieto M.A.,Simal-Gandara J.
Secondary aroma: Influence of wine microorganisms in their aroma profile
Foods, 10, , 2021

Fraga-Corral M.,Otero P.,Echave J.,Garcia-Oliveira P.,Carpena M.,Jarboui A.,Nuñez-Estevez B.,Simal-Gandara J.,Prieto M.A.
By-products of agri-food industry as tannin-rich sources: A review of tannins’ biological activities and their potential for valorization
Foods, 10, , 2021

Vilariño N.,Louzao M.C.,Fraga M.,Botana L.M.
From science to policy: Dynamic adaptation of legal regulations on aquatic biotoxins
Climate Change and Marine and Freshwater Toxins, 607-654, 2020

Garcia-Oliveira P.,Fraga-Corral M.,Pereira A.G.,Lourenço-Lopes C.,Jimenez-Lopez C.,Prieto M.A.,Simal-Gandara J.
Scientific basis for the industrialization of traditionally used plants of the Rosaceae family
Food Chemistry, 330, , 2020

Gullón P.,Gullón B.,Astray G.,Carpena M.,Fraga-Corral M.,Prieto M.A.,Simal-Gandara J.
Valorization of by-products from olive oil industry and added-value applications for innovative functional foods
Food Research International, 137, , 2020

Pereira A.G.,Fraga-Corral M.,Garciá-Oliveira P.,Jimenez-Lopez C.,Lourenço-Lopes C.,Carpena M.,Otero P.,Gullón P.,Prieto M.A.,Simal-Gandara J.
Culinary and nutritional value of edible wild plants from northern Spain rich in phenolic compounds with potential health benefits
Food and Function, 11, 8493-8515, 2020

Silva A.,Silva S.A.,Lourenço-Lopes C.,Jimenez-Lopez C.,Carpena M.,Gullón P.,Fraga-Corral M.,Domingues V.F.,Fátima Barroso M.,Simal-Gandara J.,Prieto M.A.
Antibacterial use of macroalgae compounds against foodborne pathogens
Antibiotics, 9, 1-41, 2020

Lourenço-Lopes C.,Fraga-Corral M.,Jimenez-Lopez C.,Pereira A.G.,Garcia-Oliveira P.,Carpena M.,Prieto M.A.,Simal-Gandara J.
Metabolites from macroalgae and its applications in the cosmetic industry: A circular economy approach
Resources, 9, , 2020

Lourenço-Lopes C.,Garcia-Oliveira P.,Carpena M.,Fraga-Corral M.,Jimenez-Lopez C.,Pereira A.G.,Prieto M.A.,Simal-Gandara J.
Scientific approaches on extraction, purification and stability for the commercialization of fucoxanthin recovered from brown algae
Foods, 9, , 2020

Jimenez-Lopez C.,Fraga-Corral M.,Carpena M.,García-Oliveira P.,Echave J.,Pereira A.G.,Lourenço-Lopes C.,Prieto M.A.,Simal-Gandara J.
Agriculture waste valorisation as a source of antioxidant phenolic compounds within a circular and sustainable bioeconomy
Food and Function, 11, 4853-4877, 2020

Fraga-Corral M.,García-Oliveira P.,Pereira A.G.,Lourenço-Lopes C.,Jimenez-Lopez C.,Prieto M.A.,Simal-Gandara J.
Technological application of tannin-based extracts
Molecules, 25, , 2020

Pereira A.G.,Jimenez-Lopez C.,Fraga M.,Lourenço-Lopes C.,Garcíaoliveira P.,Lorenzo J.M.,Perez-Lamela C.,Prieto M.A.,Simal-Gandara J.
Extraction, properties, and applications of bioactive compounds obtained from microalgae
Current Pharmaceutical Design, 26, 1929-1950, 2020

Abal P.,Louzao M.,Fraga M.,Vilariño N.,Ferreiro S.,Vieytes M.,Botana L.
Absorption and Effect of Azaspiracid-1 over the Human Intestinal Barrier
Cellular Physiology and Biochemistry, 43, 136-146, 2017

Fraga M.,Vilariño N.,Louzao M.C.,Molina L.,López Y.,Poli M.,Botana L.M.
First Identification of Palytoxin-Like Molecules in the Atlantic Coral Species Palythoa canariensis
Analytical Chemistry, 89, 7438-7446, 2017

Rodriguez I.,Fraga M.,Alfonso A.,Guillebault D.,Medlin L.,Baudart J.,Jacob P.,Helmi K.,Meyer T.,Breitenbach U.,Holden N.M.,Boots B.,Spurio R.,Cimarelli L.,Mancini L.,Marcheggiani S.,Albay M.,Akcaalan R.,Köker L.,Botana L.M.
Monitoring of freshwater toxins in European environmental waters by using novel multi-detection methods
Environmental Toxicology and Chemistry, 36, 645-654, 2017

Fraga M.,Vilariño N.,Louzao M.C.,Fernández D.A.,Poli M.,Botana L.M.
Detection of palytoxin-like compounds by a flow cytometry-based immunoassay supported by functional and analytical methods
Analytica Chimica Acta, 903, 1-12, 2016

Louzao M.,Fernández D.,Abal P.,Fraga M.,Vilariño N.,Vieytes M.,Botana L.
Diarrhetic effect of okadaic acid could be related with its neuronal action: Changes in neuropeptide Y
Toxicology Letters, 237, 151-160, 2015

Carmen Louzao M.,Fraga M.,Vilariño N.
Pharmacology of palytoxins and ostreocins
Phycotoxins: Chemistry and Biochemistry: Second Edition, 113-135, 2015

Fernández D.,Louzao M.,Vilariño N.,Fraga M.,Espiña B.,Vieytes M.,Botana L.
Evaluation of the intestinal permeability and cytotoxic effects of cylindrospermopsin
Toxicon, 91, 23-34, 2014

Fraga M.,Vilariño N.,Louzao M.C.,Rodríguez L.P.,Alfonso A.,Campbell K.,Elliott C.T.,Taylor P.,Ramos V.,Vasconcelos V.,Botana L.M.
Multi-detection method for five common microalgal toxins based on the use of microspheres coupled to a flow-cytometry system
Analytica Chimica Acta, 850, 57-64, 2014

Fernández D.,Louzao M.,Fraga M.,Vilariño N.,Vieytes M.,Botana L.
Experimental basis for the high oral toxicity of dinophysistoxin 1: A comparative study of DSP
Toxins, 6, 211-228, 2013

Vilariño N.,Louzao M.C.,Fraga M.,Rodríguez L.P.,Botana L.M.
Innovative detection methods for aquatic algal toxins and their presence in the food chain Rapid Detection in Food and Feed
Analytical and Bioanalytical Chemistry, 405, 7719-7732, 2013

Fraga M.,Vilariño N.,Louzao M.C.,Rodríguez P.,Campbell K.,Elliott C.T.,Botana L.M.
Multidetection of paralytic, diarrheic, and amnesic shellfish toxins by an inhibition immunoassay using a microsphere-flow cytometry system
Analytical Chemistry, 85, 7794-7802, 2013

Fernández D.A.,Louzao M.C.,Vilariño N.,Espiña B.,Fraga M.,Vieytes M.R.,Román A.,Poli M.,Botana L.M.
The kinetic, mechanistic and cytomorphological effects of palytoxin in human intestinal cells (Caco-2) explain its lower-than-parenteral oral toxicity
FEBS Journal, 280, 3906-3919, 2013

Fraga M.,Vilariño N.,Louzao M.C.,Campbell K.,Elliott C.T.,Kawatsu K.,Vieytes M.R.,Botana L.M.
Detection of paralytic shellfish toxins by a solid-phase inhibition immunoassay using a microsphere-flow cytometry system
Analytical Chemistry, 84, 4350-4356, 2012